BindingDB BDBM50401152 CHEMBL2205766

BDBM50401152 CHEMBL2205766

SMILES CC(C)(C)NS(=O)(=O)c1cncc(c1)-c1ccn2nc(N)nc2c1

InChI Key InChIKey=IVYWKCAOPCHVMX-UHFFFAOYSA-N

Data 164 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50401152

Serine/threonine-protein kinase TAO2(Homo sapiens (Human))
Cellzome

Curated by ChEMBL

BDBM50401152(CHEMBL2205766)

IC50: <1.00E+4nMAssay Description:Inhibition of TAOK2More data for this Ligand-Target Pair

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Filter my 164 hits

Targets 156▿
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 2
- Mitogen-activated protein kinase 14 2
- Casein kinase II subunit alpha 2
- Casein kinase II subunit alpha' 2
- Mitogen-activated protein kinase 8 2
- Cyclin-G-associated kinase 1
- Tyrosine-protein kinase Tec 1
- Tyrosine-protein kinase JAK1 1
- BMP-2-inducible protein kinase 1
- Tyrosine-protein kinase FRK 1
- LIM domain kinase 1 1
- LIM domain kinase 2 1
- Hepatocyte growth factor receptor 1
- Non-receptor tyrosine-protein kinase TYK2 1
- Serine/threonine-protein kinase B-raf 1
- Serine/threonine-protein kinase Nek9 1
- Glycogen synthase kinase-3 alpha 1
- Glycogen synthase kinase-3 beta 1
- Serine-protein kinase ATM 1
- AP2-associated protein kinase 1 1
- Serine/threonine-protein kinase Nek2 1
- Macrophage-stimulating protein receptor 1
- Serine/threonine-protein kinase SIK3 [59-1321] 1
- Protein kinase C theta type 1
- Dual specificity mitogen-activated protein kinase kinase 2 1
- Serine/threonine-protein kinase PAK 4 1
- Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 1
- Dual specificity mitogen-activated protein kinase kinase 1 1
- Tyrosine-protein kinase JAK2 1
- MAP/microtubule affinity-regulating kinase 4 1
- Proto-oncogene tyrosine-protein kinase receptor Ret 1
- Dual specificity mitogen-activated protein kinase kinase 5 1
- Casein kinase I isoform gamma-3 1
- Casein kinase I isoform epsilon 1
- Casein kinase I isoform gamma-1 1
- Ephrin type-A receptor 3 1
- Ephrin type-A receptor 2 1
- Tyrosine-protein kinase BTK 1
- Eukaryotic translation initiation factor 2-alpha kinase 1 1
- Serine/threonine-protein kinase mTOR 1
- Tyrosine-protein kinase ITK/TSK 1
- Bone morphogenetic protein receptor type-1A 1
- Activin receptor type-1 1
- Tyrosine-protein kinase Blk 1
- Receptor-interacting serine/threonine-protein kinase 2 1
- Serine/threonine-protein kinase 16 1
- Epidermal growth factor receptor 1
- Non-receptor tyrosine-protein kinase TNK1 1
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon 1
- Phosphoinositide 3-kinase regulatory subunit 4 1
- Receptor-interacting serine/threonine-protein kinase 3 1
- Serine/threonine-protein kinase NLK 1
- Integrin-linked protein kinase 1
- Phosphatidylinositol 3-kinase catalytic subunit type 3 1
- Wee1-like protein kinase 1
- Casein kinase I isoform delta 1
- Protein kinase C beta type 1
- Tyrosine-protein kinase Lyn 1
- Dual specificity testis-specific protein kinase 2 1
- Focal adhesion kinase 1 1
- Dual specificity testis-specific protein kinase 1 1
- Cyclin-dependent kinase 2 1
- Cyclin-dependent kinase 1 1
- Ephrin type-B receptor 4 1
- Ephrin type-B receptor 2 1
- Activated CDC42 kinase 1 1
- Ephrin type-B receptor 6 1
- MAP kinase-activated protein kinase 3 1
- Epithelial discoidin domain-containing receptor 1 1
- Phosphatidylinositol 4-kinase beta 1
- Tyrosine-protein kinase Fer 1
- Serine/threonine-protein kinase D2 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-2 1
- Calcium/calmodulin-dependent protein kinase type II subunit delta 1
- Cyclin-dependent kinase 9 1
- Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 1
- Cyclin-dependent kinase 7 1
- Serine/threonine-protein kinase TAO1 1
- Cyclin-dependent kinase 6 1
- Cyclin-dependent kinase 5 1
- Calcium/calmodulin-dependent protein kinase kinase 1 1
- Serine/threonine-protein kinase TAO3 1
- Calcium/calmodulin-dependent protein kinase kinase 2 1
- Serine/threonine-protein kinase TAO2 1
- Mitogen-activated protein kinase kinase kinase kinase 2 1
- Mitogen-activated protein kinase kinase kinase kinase 3 1
- Mitogen-activated protein kinase kinase kinase kinase 1 1
- Protein-tyrosine kinase 6 1
- Mitogen-activated protein kinase kinase kinase kinase 5 1
- Serine/threonine-protein kinase ATR 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-1 1
- Activin receptor type-1B 1
- Bromodomain-containing protein 4 1
- Bromodomain-containing protein 3 1
- Mitogen-activated protein kinase kinase kinase 5 1
- Interleukin-1 receptor-associated kinase 1 1
- Bromodomain-containing protein 2 1
- Tyrosine-protein kinase ABL2 1
- Tyrosine-protein kinase ABL1 1
- Interleukin-1 receptor-associated kinase 3 1
- Mitogen-activated protein kinase kinase kinase 2 1
- Atypical kinase COQ8B, mitochondrial 1
- Serine/threonine-protein kinase A-Raf 1
- Mitogen-activated protein kinase kinase kinase 1 1
- Mitogen-activated protein kinase kinase kinase 4 1
- Mitogen-activated protein kinase kinase kinase 3 1
- Proto-oncogene tyrosine-protein kinase Src 1
- Activin receptor type-2B 1
- Tyrosine-protein kinase Fes/Fps 1
- Serine/threonine-protein kinase SIK2 1
- Activin receptor type-2A 1
- Serine/threonine-protein kinase ULK3 1
- Mitogen-activated protein kinase 1 1
- Serine/threonine-protein kinase 3 1
- 3-phosphoinositide-dependent protein kinase 1 1
- Tyrosine-protein kinase Lck 1
- Mitogen-activated protein kinase 3 1
- Serine/threonine-protein kinase 4 1
- Serine/threonine-protein kinase 17B 1
- Dual specificity protein kinase CLK1 1
- Protein kinase C delta type 1
- Dual specificity protein kinase CLK2 1
- Protein-tyrosine kinase 2-beta 1
- Calcium/calmodulin-dependent protein kinase type II subunit gamma 1
- Calcium/calmodulin-dependent protein kinase type IV 1
- Serine/threonine-protein kinase N1 1
- Tyrosine-protein kinase SYK 1
- Ribosomal protein S6 kinase alpha-3 1
- Ribosomal protein S6 kinase alpha-1 1
- Serine/threonine-protein kinase TBK1 1
- Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 1
- Calcium/calmodulin-dependent protein kinase type 1D 1
- Serine/threonine-protein kinase RIO2 1
- Aurora kinase B 1
- Tyrosine-protein kinase Fgr 1
- Aurora kinase A 1
- Fibroblast growth factor receptor 1 1
- Mitogen-activated protein kinase kinase kinase 20 1
- Atypical kinase COQ8A, mitochondrial 1
- Serine/threonine-protein kinase PLK4 1
- Mitogen-activated protein kinase 11 1
- Casein kinase I isoform alpha 1
- Tyrosine-protein kinase Fyn 1
- Tyrosine-protein kinase CSK 1
- Protein kinase C alpha type 1
- eIF-2-alpha kinase GCN2 1
- Ribosomal protein S6 kinase alpha-4 1
- Ribosomal protein S6 kinase alpha-5 1
- Maternal embryonic leucine zipper kinase 1
- Phosphatidylinositol 4-kinase alpha 1
- Serine/threonine-protein kinase MARK2 1
- Tyrosine-protein kinase Yes 1
- Mitogen-activated protein kinase kinase kinase 11 1
Publications 1▿
- Bioorg Med Chem Lett 22: 4613-8 (2012) 164
Institutions 1▿
- Cellzome 164
Affinity: 13 to 5.0E+7 nM▿
- IC50 164
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 0